19 Comments
User's avatar
Bitcoin Awareness's avatar

Where to find about doses of T3 and T4 to use and adjust?

Master Metabolism's avatar

Ray Peat and Paul Robinson are the best I have come across on that topic. Broda Barnes, though he used NDT (which has both in a protein). I have an educational course/community, too. skool.com/thyroid

Bitcoin Awareness's avatar

Thanks!

Outlawed In Church's avatar

I've been taking T3/T4 for years. First in the form of Naturethroid, and then Cynoplus. My numbers are almost always in a good range and my cholesterol came down from 300+ to around 225. My reverse T3 is on the low end. Nevertheless I still wake up with body temp around 96.4. I've tried a small amount of Cynoplus in the evening but it seems to make my sleep even worse

Master Metabolism's avatar

Aside from thyroid, it could be a diet/lifestyle issue. Not enough energy to sleep, or something irritating the gut.

J. Harris's avatar

John,

Look into Dr. Sarah Myhill’s work on Upper Fermenting Gut. The UFG drives a lot of DISease, including hypothyroid. She treats the UFG first with VitC, along with Paleo Keto and also uses Lugol’s Iodine to correct iodine deficiency at the cellular level. I must say from my experience and decades of chasing symptoms, including hypothyroid using Naturthroid/Amour, this proctor has given me the best and quickest results to healing!

Outlawed In Church's avatar

Thanks for commenting. I will look into Vitamin C and Iodine, but Paleo (low carb) was the beginning of all this trouble for me. For some people low carb seems to down regulate thyroid

J. Harris's avatar

John, don’t discount the fact that when your body starts burning its own toxic loaded fat, it puts more of a burden on detox pathways, especially the liver which affects thyroid function. In addition, must of us have a cellular magnesium deficiency as well as Vit D deficiency. Vit D is needed for magnesium absorption as well as having a sterile upper gut. Due to the fear monger of of the sun, as well as what latitude one lives in, we don’t get enough Vit D naturally, thus the need to supplement. Anyhoot…all this plays into our metabolic health, including thyroid. I agree, once the UFG is corrected, iodine and magnesium cellular level saturated, eating good carbs seasonally makes sense.

Outlawed In Church's avatar

Thank you for the additional input. Thankfully, I have been able to optimize my vitamin D levels with sun and supplementation. Oddly enough, every single time I have tried to take magnesium, it seems to make my hypothyroid symptoms worse. And I have tried every form of magnesium available

Master Metabolism's avatar

Yeah, beware the low carb or high protein diet. Excessive doses of iodine increase thyroid hormones in a lot of people but it's risky.

Outlawed In Church's avatar

Is there a "non risky dose" we always have som Lugol's iodine around

Amanda Kennemore's avatar

Synthroid didn’t help my symptoms (cold and tired being the main ones) but I took it out of compliance. After many years, I developed arrhythmia. My doctor lowered my dose, and it resolved. I moved cities, and eventually developed arrhythmia at the new dose. Saw an endocrinologist, got labs, but because he was happy with the TSH, he kept me at the same dose! I just stopped taking it. Didn’t notice any difference in thyroid symptoms, honestly. But the arrhythmia resolved. In time I saw another endocrinologist (PCPs always freak out seeing my TSH and refer me) but once TSH was in the target range, she was 100% satisfied. Whereas for me, I had no beneficial change to symptoms, but developed arrhythmia again. The blank looks, you know? The little shrug. I gave up on it. I haven’t taken T4 for 7 years, a little while back I tried supplementing a little iodine, but got arrhythmia. My hypothyroid symptoms have grown worse lately. Not sure if I should try again, don’t know if there’s an answer. Have you heard of something like this?

Master Metabolism's avatar

Yes. Arrhythmia can be from too much or too litle thyroid hormone (T3). Neither synthroid nor iodine are good ways of correcting that. Testing prescription NDT is the first thing I would do, assuming the bloods indicate hypo and not hyper.

Amanda Kennemore's avatar

Thank you for your response! Very good to know

Tom's avatar

Watch Rocky (yes the movie), then do what he does (ish). The odds will favor you. Obviously there’s no guarantee. 🤷

Rose Sybil's avatar

What is the ratio of t4 to t3 taken? Also wouldn’t desiccated thyroid provide that low of a t3 dose?

Master Metabolism's avatar

There is some T3 in NDT USP. Usually the ratio in that is good enough. Some people need higher T3:T4 and some need T3 only.